Bird Flu Alarm



Understanding Avian Influenza

Administration of Antiviral Drugs for Prophylaxis

Administration of Antiviral Drugs for Prophylaxis


Workers should receive an influenza antiviral drug daily for the duration of time during which direct contact with infected poultry or contaminated surfaces occurs. The choice of antiviral drug should be based on sensitivity testing when possible. In the absence of sensitivity testing, a neuraminidase inhibitor (oseltamavir) is the first choice since the likelihood is smaller that the virus will be resistant to this class of antiviral drugs than to amantadine or rimantadine. Also, please note the January 14, 2006 CDC Health Alert Notice (HAN), in which CDC recommends that neither amantadine nor rimantadine be used for the treatment or prevention (prophylaxis) of influenza A in the United States for the remainder of the 2005-06 influenza season. For further information about the use of antiviral drugs for influenza, see "Prevention and Control of Influenza". Recommendations of the Advisory Committee on Immunization Practices (ACIP)." MMWR 2003; 52(RR08): 1-36. Available at www.cdc.gov/mmwr/preview/mmwrhtml/rr5208a1.htm.